Mitochondrial tRNAAla C5601T mutation may modulate the clinical expression of tRNAMet A4435G mutation in a Han Chinese family with hypertension

Mutations in mitochondrial DNA, especially in mitochondrial tRNA (mt-tRNA) genes, are the important causes for maternally inherited hypertension. In this study, we reported the clinical, genetic, and molecular characterization of a Han Chinese family with hypertension. Most strikingly, this family e...

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Bibliographic Details
Main Authors: Ping Zheng, Shiliang Li, Chun Liu, Zhengbiao Zha, Xiang Wei, Yuan Yuan
Format: Article
Language:English
Published: Taylor & Francis Group 2018-08-01
Series:Clinical and Experimental Hypertension
Subjects:
Online Access:http://dx.doi.org/10.1080/10641963.2017.1411497