Ginkgo Flavonol Glycosides or Ginkgolides Tend to Differentially Protect Myocardial or Cerebral Ischemia–Reperfusion Injury via Regulation of TWEAK-Fn14 Signaling in Heart and Brain

Ginkgo Flavonol Glycosides or Ginkgolides Tend to Differentially Protect Myocardial or Cerebral Ischemia–Reperfusion Injury via Regulation of TWEAK-Fn14 Signaling in Heart and Brain

Shuxuening injection (SXNI), one of the pharmaceutical preparations of Ginkgo biloba extract, has significant effects on both ischemic stroke and heart diseases from bench to bedside. Its major active ingredients are ginkgo flavonol glycosides (GFGs) and ginkgolides (GGs). We have previously reported...

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Bibliographic Details
Main Authors: Guangxu Xiao, Ming Lyu, Yule Wang, Shuang He, Xinyan Liu, Jingyu Ni, Lan Li, Guanwei Fan, Jihong Han, Xiumei Gao, Xiaoying Wang, Yan Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Pharmacology
Subjects:
Shuxuening injection
ginkgo flavonol glycosides
ginkgolides
myocardial ischemia—reperfusion injury
cerebral ischemia—reperfusion injury
TWEAK–Fn14 signaling
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00735/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00735/full

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