Downregulation of N6-methyladenosine-modified LINC00641 promotes EMT, but provides a ferroptotic vulnerability in lung cancer

Abstract The prognosis of lung cancer is poor with few effective therapies. Targeting ferroptosis is a new promising strategy for cancer therapy. LINC00641 has been involved in several cancers, however, its specific roles in lung cancer treatment remain largely unknown. Here, we reported that LINC00...

Full description

Bibliographic Details
Main Authors: Shu Xi, Dao-Jing Ming, Jin-Hui Zhang, Meng-Meng Guo, Shuang-Ying Wang, Yi Cai, Meng-Yang Liu, Dan-Qi Wang, Yi-Jie Zhang, Yafei Li, Shuai Yuan
Format: Article
Language:English
Published: Nature Publishing Group 2023-06-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-05880-3