Exploring the mechanisms underlying excitation/inhibition imbalance in human iPSC-derived models of ASD

Abstract Autism spectrum disorder (ASD) is a range of neurodevelopmental disorders characterized by impaired social interaction and communication, and repetitive or restricted behaviors. ASD subjects exhibit complex genetic and clinical heterogeneity, thus hindering the discovery of pathophysiologic...

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Bibliographic Details
Main Authors: Lorenza Culotta, Peter Penzes
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Molecular Autism
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13229-020-00339-0