Biosilicated collagen/β-tricalcium phosphate composites as a BMP-2-delivering bone‐graft substitute for accelerated craniofacial bone regeneration

Biosilicated collagen/β-tricalcium phosphate composites as a BMP-2-delivering bone‐graft substitute for accelerated craniofacial bone regeneration

Abstract Background Bioceramic β-tricalcium phosphate (β-TCP) is used as a bone-grafting material and a therapeutic drug carrier for treatment of bone defects in the oral and maxillofacial regions due to the osteoconductivity and biocompatibility. However, the low mechanical strength and limited ost...

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Bibliographic Details
Main Authors: Dong Keon Lee, Mi-Ran Ki, Euy Hyun Kim, Chang-Joo Park, Jae Jun Ryu, Hyon Seok Jang, Seung Pil Pack, Yun Kee Jo, Sang Ho Jun
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2021-04-01
Series:Biomaterials Research
Subjects:
Osteoinductive bone substitute
Collagen/β-TCP composite
Biosilicification
Bone morphogenetic protein-2 (BMP-2)
Biomimetic materials
Online Access:https://doi.org/10.1186/s40824-021-00214-w

Internet

https://doi.org/10.1186/s40824-021-00214-w

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