Protective Effects of Nucleobinding-2 After Cerebral Ischemia Via Modulating Bcl-2/Bax Ratio and Reducing Glial Fibrillary Acid Protein Expression

Protective Effects of Nucleobinding-2 After Cerebral Ischemia Via Modulating Bcl-2/Bax Ratio and Reducing Glial Fibrillary Acid Protein Expression

Introduction: Nucleobinding-2 (NUCB2) or nesfatin-1, a newly identified anorexigenic peptide, has antioxidant, anti-inflammatory, and anti-apoptotic properties. Brain ischemia-reperfusion induces irreversible damages, especially in the hippocampus area. However, the therapeutic effects of NUCB2 have...

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Bibliographic Details
Main Authors: Soheila Erfani, Ali Moghimi, Nahid Aboutaleb, Mehdi Khaksari
Format: Article
Language:English
Published: Iran University of Medical Sciences 2019-09-01
Series:Basic and Clinical Neuroscience
Subjects:
nucleobinding-2 (nucb2)
nesfatin-1
apoptosis
astrogliosis
hippocampus
ischemia
Online Access:http://bcn.iums.ac.ir/article-1-1221-en.html

Internet

http://bcn.iums.ac.ir/article-1-1221-en.html

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