Stochastic Sensing of Polynucleotides Using Patterned Nanopores

The effect of the microscopic structure of a pore on polymer translocation is studied using Langevin dynamics simulation, and the consequence of introducing patterned stickiness inside the pore is investigated. It is found that the translocation process is extremely sensitive to the detailed structu...

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Bibliographic Details
Main Authors: Jack A. Cohen, Abhishek Chaudhuri, Ramin Golestanian
Format: Article
Language:English
Published: American Physical Society 2012-04-01
Series:Physical Review X
Online Access:http://doi.org/10.1103/PhysRevX.2.021002