Quantitative muscle MRI captures early muscle degeneration in calpainopathy

Abstract To evaluate differences in qMRI parameters of muscle diffusion tensor imaging (mDTI), fat-fraction (FF) and water T2 time in leg muscles of calpainopathy patients (LGMD R1/D4) compared to healthy controls, to correlate those findings to clinical parameters and to evaluate if qMRI parameters...

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Bibliographic Details
Main Authors: Johannes Forsting, Marlena Rohm, Martijn Froeling, Anne-Katrin Güttsches, Nicolina Südkamp, Andreas Roos, Matthias Vorgerd, Lara Schlaffke, Robert Rehmann
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-23972-6