Vasoconstrictor and Pressor Effects of Des-Aspartate-Angiotensin I in Rat

Vasoconstrictor and Pressor Effects of Des-Aspartate-Angiotensin I in Rat

This study investigated the vasoactive effects of des-aspartate-angiotensin-I (DAA-I) in male Wistar rats on whole body vascular bed, isolated perfused kidneys, and aortic rings. Dose–response curves to DAA-I were compared with those to angiotensin II (Ang II). The Ang II-type-1 (AT1) receptor block...

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Bibliographic Details
Main Authors: Rosemary Wangensteen, Manuel Gómez-Guzmán, Inmaculada Banegas, Isabel Rodríguez-Gómez, Rosario Jiménez, Juan Duarte, Joaquín García-Estañ, Félix Vargas
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Biomedicines
Subjects:
renin-angiotensin system
des-aspartate-angiotensin I
vascular reactivity
kidney
hypertension
Online Access:https://www.mdpi.com/2227-9059/10/6/1230

Internet

https://www.mdpi.com/2227-9059/10/6/1230

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