Unravelling the genetic architecture of human complex traits through whole genome sequencing

Whole genome sequencing has enabled new insights into the genetic architecture of complex traits, especially through access to low-frequency and rare variation. This Comment highlights the key contributions from this technology and discusses considerations for its use and future perspectives.

Bibliographic Details
Main Authors: Ozvan Bocher, Cristen J. Willer, Eleftheria Zeggini
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-39259-x