<i>Mycobacterium tuberculosis</i> Rv0580c Impedes the Intracellular Survival of Recombinant Mycobacteria, Manipulates the Cytokines, and Induces ER Stress and Apoptosis in Host Macrophages via NF-κB and p38/JNK Signaling

<i>Mycobacterium tuberculosis</i> Rv0580c Impedes the Intracellular Survival of Recombinant Mycobacteria, Manipulates the Cytokines, and Induces ER Stress and Apoptosis in Host Macrophages via NF-κB and p38/JNK Signaling

The <i>Mycobacterium tuberculosis</i> (<i>M. tb</i>) genome encodes a large number of hypothetical proteins, which need to investigate their role in physiology, virulence, pathogenesis, and host interaction. To explore the role of hypothetical protein Rv0580c, we constructed...

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Bibliographic Details
Main Authors: Md Kaisar Ali, Lambert Nzungize, Khushnood Abbas, Nzaou Stech Anomene Eckzechel, M. A. Abo-kadoum, Ulrich Aymard Ekomi Moure, Mohammed Asaad, Aftab Alam, Junqi Xu, Jianping Xie
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Pathogens
Subjects:
<i>Mycobacterium tuberculosis</i>
Rv0580c
cell wall
cytokines
apoptosis
Online Access:https://www.mdpi.com/2076-0817/10/2/143

Internet

https://www.mdpi.com/2076-0817/10/2/143

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