Analysis of REST binding sites with canonical and non-canonical motifs in human cell lines
Abstract Background Repressor element 1 (RE1) silencing transcription factor (REST) is a transcriptional repressor abundantly expressed in aging human brains. It is known to regulate genes associated with oxidative stress, inflammation, and neurological disorders by binding to a canonical form of se...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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BMC
2024-04-01
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| Series: | BMC Medical Genomics |
| Online Access: | https://doi.org/10.1186/s12920-024-01860-4 |