Structural and functional analysis of a platelet-activating lysophosphatidylcholine of Trypanosoma cruzi.

Structural and functional analysis of a platelet-activating lysophosphatidylcholine of Trypanosoma cruzi.

Trypanosoma cruzi is the causative agent of the life-threatening Chagas disease, in which increased platelet aggregation related to myocarditis is observed. Platelet-activating factor (PAF) is a potent intercellular lipid mediator and second messenger that exerts its activity through a PAF-specific...

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Main Authors: Felipe Gazos-Lopes, Mauricio M Oliveira, Lucas V B Hoelz, Danielle P Vieira, Alexandre F Marques, Ernesto S Nakayasu, Marta T Gomes, Nasim G Salloum, Pedro G Pascutti, Thaïs Souto-Padrón, Robson Q Monteiro, Angela H Lopes, Igor C Almeida
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-08-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4125143?pdf=render

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http://europepmc.org/articles/PMC4125143?pdf=render

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