A high-throughput screening assay to identify inhibitory antibodies targeting alphavirus release

Abstract Background Several studies have demonstrated neutralizing antibodies to be highly effective against alphavirus infection in animal models, both prophylactically and remedially. In most studies, neutralizing antibodies have been evaluated for their ability to block viral entry in vitro but r...

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Bibliographic Details
Main Authors: Anushka Ramjag, Sergej Cutrone, Kai Lu, Christine Crasto, Jing Jin, Sonia Bakkour, Christine V. F. Carrington, Graham Simmons
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Virology Journal
Subjects:
Online Access:https://doi.org/10.1186/s12985-022-01906-y