Gene editing in clinical isolates of Candida parapsilosis using CRISPR/Cas9

Abstract Candida parapsilosis is one of the most common causes of candidiasis, particularly in the very young and the very old. Studies of gene function are limited by the lack of a sexual cycle, the diploid genome, and a paucity of molecular tools. We describe here the development of a plasmid-base...

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Bibliographic Details
Main Authors: Lisa Lombardi, Siobhán A. Turner, Fang Zhao, Geraldine Butler
Format: Article
Language:English
Published: Nature Portfolio 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-08500-1