Retrotransposon-Encoded Reverse Transcriptase in the Genesis, Progression and Cellular Plasticity of Human Cancer

LINE-1 (Long Interspersed Nuclear Elements) and HERVs (Human Endogenous Retroviruses) are two families of autonomously replicating retrotransposons that together account for about 28% of the human genome. Genes harbored within LINE-1 and HERV retrotransposons, particularly those encoding the reverse...

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Bibliographic Details
Main Authors: Corrado Spadafora, Paola Sinibaldi-Vallebona, Claudia Matteucci
Format: Article
Language:English
Published: MDPI AG 2011-03-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/3/1/1141/