Glucagon-like peptide-1 attenuates diabetes-associated osteoporosis in ZDF rat, possibly through the RAGE pathway

Glucagon-like peptide-1 attenuates diabetes-associated osteoporosis in ZDF rat, possibly through the RAGE pathway

Abstract Background Diabetes-associated osteoporosis are partly caused by accumulation of advanced glycation endproducts (AGEs). Glucagon-like peptide-1 (GLP-1) has been shown to regulate bone turnover. Here we explore whether GLP-1 receptor agonist (GLP1RA) can have a beneficial effect on bone in d...

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Bibliographic Details
Main Authors: Yanzhen Cheng, Peng Liu, Qianru Xiang, Jiamin Liang, Huafeng Chen, Hua Zhang, Li Yang
Format: Article
Language:English
Published: BMC 2022-05-01
Series:BMC Musculoskeletal Disorders
Subjects:
Glucagon-like peptide-1
Advanced glycation endproducts
Diabetes
Osteoporosis
Liraglutide
Online Access:https://doi.org/10.1186/s12891-022-05396-5

Internet

https://doi.org/10.1186/s12891-022-05396-5

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