Pitx2c orchestrates embryonic axis extension via mesendodermal cell migration

Pitx2c orchestrates embryonic axis extension via mesendodermal cell migration

Pitx2c, a homeodomain transcription factor, is classically known for its left-right patterning role. However, an early wave of pitx2 expression occurs at the onset of gastrulation in several species, indicating a possible earlier role that remains relatively unexplored. Here we show that in zebrafis...

Full description

Bibliographic Details
Main Authors: Michelle M Collins, Hans-Martin Maischein, Pascale Dufourcq, Marine Charpentier, Patrick Blader, Didier YR Stainier
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-06-01
Series:eLife
Subjects:
Pitx2c
gastrulation
chemokine signaling
integrin-fibronectin interaction
cell migration
Online Access:https://elifesciences.org/articles/34880

Internet

https://elifesciences.org/articles/34880

Similar Items