GSK-3 and Wnt signaling in neurogenesis and bipolar disorder

The Wnt signaling pathway is critical for development of the mammalian central nervous system and regulates diverse processes throughout adulthood, including adult neurogenesis. Glycogen Synthase Kinase-3 (GSK-3) antagonizes the Wnt pathway and therefore also plays a central role in neural developme...

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Bibliographic Details
Main Authors: Alexander J Valvezan, Peter S Klein
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-01-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2012.00001/full