Genetic control of ATGL-mediated lipolysis modulates adipose triglyceride stores in leptin-deficient mice
Dissecting the genetics of complex traits such as obesity allows the identification of causal genes for disease. Here, we show that the BALB/c mouse strain carries genetic variants that confer resistance to obesity induced by leptin-deficiency or a high-fat diet (HFD). We set out to identify the phy...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2012-05-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520392269 |