In‐depth proteomic analysis reveals unique subtype‐specific signatures in human small‐cell lung cancer

In‐depth proteomic analysis reveals unique subtype‐specific signatures in human small‐cell lung cancer

Abstract Background Small‐cell lung cancer (SCLC) molecular subtypes have been primarily characterized based on the expression pattern of the following key transcription regulators: ASCL1 (SCLC‐A), NEUROD1 (SCLC‐N), POU2F3 (SCLC‐P) and YAP1 (SCLC‐Y). Here, we investigated the proteomic landscape of...

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Main Authors: Beáta Szeitz, Zsolt Megyesfalvi, Nicole Woldmar, Zsuzsanna Valkó, Anna Schwendenwein, Nándor Bárány, Sándor Paku, Viktória László, Helga Kiss, Edina Bugyik, Christian Lang, Attila Marcell Szász, Luciana Pizzatti, Krisztina Bogos, Mir Alireza Hoda, Konrad Hoetzenecker, György Marko‐Varga, Peter Horvatovich, Balázs Döme, Karin Schelch, Melinda Rezeli
Format: Article
Language:English
Published: Wiley 2022-09-01
Series:Clinical and Translational Medicine
Subjects:
diagnostic biomarkers
molecular targets
proteomics
secretome
small‐cell lung cancer
subtype
Online Access:https://doi.org/10.1002/ctm2.1060

Internet

https://doi.org/10.1002/ctm2.1060

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