Recent advances in mRNA-LNP therapeutics: immunological and pharmacological aspects

Recent advances in mRNA-LNP therapeutics: immunological and pharmacological aspects

Abstract In the last decade, the development of messenger RNA (mRNA) therapeutics by lipid nanoparticles (LNP) leads to facilitate clinical trial recruitment, which improves the efficacy of treatment modality to a large extent. Although mRNA-LNP vaccine platforms for the COVID-19 pandemic demonstrat...

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Bibliographic Details
Main Authors: Seyed Hossein Kiaie, Naime Majidi Zolbanin, Armin Ahmadi, Rafieh Bagherifar, Hadi Valizadeh, Fatah Kashanchi, Reza Jafari
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Journal of Nanobiotechnology
Subjects:
Lipid nanoparticles
mRNA delivery
Immunogenicity
Pharmacologic response
Dendritic cell
Immune system
Online Access:https://doi.org/10.1186/s12951-022-01478-7

Internet

https://doi.org/10.1186/s12951-022-01478-7

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