A Systematic Review of Treatment of Painful Diabetic Neuropathy by Pain Phenotype versus Treatment Based on Medical Comorbidities

BackgroundPainful diabetic neuropathy (PDN) is a serious, polymorphic, and prevalent complication of diabetes mellitus. Most PDN treatment guidelines recommend a selection of drugs based on patient comorbidities. Despite the large numbers of medications available, most randomized clinical trials (RC...

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Bibliographic Details
Main Authors: Luiz Clemente Rolim, Edina M. Koga da Silva, João Roberto De Sá, Sérgio Atala Dib
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Neurology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fneur.2017.00285/full