Plasma proenkephalin A and incident chronic kidney disease and albuminuria in the REasons for Geographic And Racial Differences in Stroke (REGARDS) cohort

Abstract Background Plasma proenkephalin A (PENK-A) is a precursor of active enkephalins. Higher blood concentrations have been associated with estimated glomerular filtration rate (eGFR) decline in European populations. Due to the significant disparity in incident chronic kidney disease (CKD) betwe...

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Main Authors: Alexander L. Bullen, Ronit Katz, Sayna Poursadrolah, Samuel A. P. Short, D. Leann Long, Katharine L. Cheung, Shilpa Sharma, Tala Al-Rousan, Alma Fregoso, Janin Schulte, Orlando M. Gutierrez, Michael G. Shlipak, Mary Cushman, Joachim H. Ix, Dena E. Rifkin
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Nephrology
Subjects:
Online Access:https://doi.org/10.1186/s12882-023-03432-7