Basic biochemical investigations as rationale for the design of original antimalarial drugs. An example of phospholipid metabolism

The future of antimalarial chemotherapy is particulary alarming in view of the spread of parasite cross-resistances to drugs that are not even structurally related. Only the availability of new pharmacological models will make it possible to select molecules with novel mechanisms of action, thus del...

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Bibliographic Details
Main Authors: Henri J. Vial, Marie L. Angelin, Nourredine Elabbadi, Michele Calas, Gerard Cordinas, Louis Giral
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 1992-01-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761992000700042