Epigenetic regulation of Parkinson’s disease risk variant GPNMB cg17274742 methylation by sex and exercise from Taiwan Biobank

BackgroundParkinson’s disease (PD) is a complex neurodegenerative disease with an elusive etiology that involves the interaction between genetic, behavioral, and environmental factors. Recently, epigenetic modifications, particularly DNA methylation, have been recognized to play an important role in...

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Bibliographic Details
Main Authors: Yen-Chung Chen, Yi-Chia Liaw, Oswald Ndi Nfor, Chih-Hsuan Hsiao, Ji-Han Zhong, Shey-Lin Wu, Yung-Po Liaw
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1235840/full