Polymer Concentration Maximizes Encapsulation Efficiency in Electrohydrodynamic Mixing Nanoprecipitation

Polymer Concentration Maximizes Encapsulation Efficiency in Electrohydrodynamic Mixing Nanoprecipitation

Encapsulation in self-assembled block copolymer (BCP) based nanoparticles (NPs) is a common approach to enhance hydrophobic drug solubility, and nanoprecipitation processes in particular can yield high encapsulation efficiency (EE). However, guiding principles for optimizing polymer, drug, and solve...

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Bibliographic Details
Main Authors: Kil Ho Lee, Faiz N. Khan, Lauren Cosby, Guolingzi Yang, Jessica O. Winter
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Nanotechnology
Subjects:
electrohydrodynamic mixing
nanoprecipitation
Hansen solubility parameters
block copolymer
drug encapsulation
micromixer
Online Access:https://www.frontiersin.org/articles/10.3389/fnano.2021.719710/full

Internet

https://www.frontiersin.org/articles/10.3389/fnano.2021.719710/full

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