Fragment-based drug discovery and biological evaluation of novel cannabinol-based inhibitors of oxytosis/ferroptosis for neurological disorders

The oxytosis/ferroptosis regulated cell death pathway is an emerging field of research owing to its pathophysiological relevance to a wide range of neurological disorders, including Alzheimer's and Parkinson's diseases and traumatic brain injury. Developing novel neurotherapeutics to inhib...

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Bibliographic Details
Main Authors: Zhibin Liang, Alec Candib, David Soriano-Castell, Wolfgang Fischer, Kim Finley, Pamela Maher
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Redox Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231724001149