An integrative approach using real-world data to identify alternative therapeutic uses of existing drugs.
Different computational approaches are employed to efficiently identify novel repositioning possibilities utilizing different sources of information and algorithms. It is critical to propose high-valued candidate-repositioning possibilities before conducting lengthy in vivo validation studies that c...
Main Authors: | Kouichi Hosomi, Mai Fujimoto, Kazutaka Ushio, Lili Mao, Juran Kato, Mitsutaka Takada |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC6177143?pdf=render |
Similar Items
-
Repurposing haloperidol for the treatment of rheumatoid arthritis: an integrative approach using data mining techniques
by: Chihiro Nakagawa, et al.
Published: (2021-09-01) -
Risk factors for amiodarone-induced thyroid dysfunction in Japan
by: Sayoko Kinoshita, et al.
Published: (2016-12-01) -
The influence of residual apixaban on bleeding complications during and after catheter ablation of atrial fibrillation
by: Yutaro Mukai, et al.
Published: (2017-10-01) -
Association between statin use and open-angle glaucoma: a nested case–control study using the Japanese claims database
by: Satoshi Yokoyama, et al.
Published: (2023-07-01) -
Evaluation of tolvaptan-associated hepatic disorder using different national pharmacovigilance databases
by: Takaya Uno, et al.
Published: (2024-10-01)