The miR-23-27-24 clusters drive lipid-associated macrophage proliferation in obese adipose tissue

Summary: Identifying molecular circuits that control adipose tissue macrophage (ATM) function is necessary to understand how ATMs contribute to tissue homeostasis and obesity-induced insulin resistance. In this study, we find that mice with a myeloid-specific knockout of the miR-23-27-24 clusters of...

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Bibliographic Details
Main Authors: Neil T. Sprenkle, Nathan C. Winn, Kaitlyn E. Bunn, Yang Zhao, Deborah J. Park, Brenna G. Giese, John J. Karijolich, K. Mark Ansel, C. Henrique Serezani, Alyssa H. Hasty, Heather H. Pua
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723009397