Enhanced self-renewal of human pluripotent stem cells by simulated microgravity
Abstract A systematic study on the biological effects of simulated microgravity (sµg) on human pluripotent stem cells (hPSC) is still lacking. Here, we used a fast-rotating 2-D clinostat to investigate the sµg effect on proliferation, self-renewal, and cell cycle regulation of hPSCs. We observed sig...
Main Authors: | S. Timilsina, T. Kirsch-Mangu, S. Werth, B. Shepard, T. Ma, L. G. Villa-Diaz |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-07-01
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Series: | npj Microgravity |
Online Access: | https://doi.org/10.1038/s41526-022-00209-4 |
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