The low-density lipoprotein receptor promotes infection of multiple encephalitic alphaviruses

Abstract Members of the low-density lipoprotein receptor (LDLR) family, including LDLRAD3, VLDLR, and ApoER2, were recently described as entry factors for different alphaviruses. However, based on studies with gene edited cells and knockout mice, blockade or abrogation of these receptors does not fu...

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Bibliographic Details
Main Authors: Hongming Ma, Lucas J. Adams, Saravanan Raju, Alan Sariol, Natasha M. Kafai, Hana Janova, William B. Klimstra, Daved H. Fremont, Michael S. Diamond
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-44624-x