Modifiable and non-modifiable risk factors of dementia on midlife cerebral small vessel disease in cognitively healthy middle-aged adults: the PREVENT-Dementia study

Modifiable and non-modifiable risk factors of dementia on midlife cerebral small vessel disease in cognitively healthy middle-aged adults: the PREVENT-Dementia study

Abstract Background Considerable overlap exists between the risk factors of dementia and cerebral small vessel disease (SVD). However, studies remain limited to older cohorts wherein pathologies of both dementia (e.g. amyloid) and SVD (e.g. white matter hyperintensities) already co-exist. In younger...

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Bibliographic Details
Main Authors: Audrey Low, Maria A. Prats-Sedano, Elizabeth McKiernan, Stephen F. Carter, James D. Stefaniak, Stefania Nannoni, Li Su, Maria-Eleni Dounavi, Graciela Muniz-Terrera, Karen Ritchie, Brian Lawlor, Lorina Naci, Paresh Malhotra, Clare Mackay, Ivan Koychev, Craig W. Ritchie, Hugh S. Markus, John T. O’Brien
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Alzheimer’s Research & Therapy
Subjects:
Alzheimer’s disease
Cerebral small vessel disease
Modifiable risk factors
APOE4
Lifestyle
Prevention
Online Access:https://doi.org/10.1186/s13195-022-01095-4

Internet

https://doi.org/10.1186/s13195-022-01095-4

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