Glutamine and Cholesterol Plasma Levels and Clinical Outcomes of Patients with Metastatic Castration-Resistant Prostate Cancer Treated with Taxanes

Glutamine and Cholesterol Plasma Levels and Clinical Outcomes of Patients with Metastatic Castration-Resistant Prostate Cancer Treated with Taxanes

Altered metabolism is a hallmark of cancer. Malignant cells metabolise glutamine to fulfil their metabolic needs. In prostate cancer, androgen receptor signalling promotes glutamine metabolism, which is also involved in cholesterol homeostasis. We aimed to determine whether the plasma glutamine leve...

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Bibliographic Details
Main Authors: Mercedes Marín-Aguilera, María V. Pereira, Natalia Jiménez, Òscar Reig, Anna Cuartero, Iván Victoria, Caterina Aversa, Laura Ferrer-Mileo, Aleix Prat, Begoña Mellado
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cancers
Subjects:
biomarkers
prostate cancer
glutamine
liquid biopsy
metabolism
taxanes
Online Access:https://www.mdpi.com/2072-6694/13/19/4960

Internet

https://www.mdpi.com/2072-6694/13/19/4960

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