Single-Cell RNA Sequencing Reveals Immuno-Oncology Characteristics of Tumor-Infiltrating T Lymphocytes in Photodynamic Therapy-Treated Colorectal Cancer Mouse Model

Single-Cell RNA Sequencing Reveals Immuno-Oncology Characteristics of Tumor-Infiltrating T Lymphocytes in Photodynamic Therapy-Treated Colorectal Cancer Mouse Model

Photodynamic therapy (PDT) has shown promise in reducing metastatic colorectal cancer (CRC); however, the underlying mechanisms remain unclear. Modulating tumor-infiltrating immune cells by PDT may be achieved, which requires the characterization of immune cell populations in the tumor microenvironm...

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Bibliographic Details
Main Authors: Eun-Ji Lee, Jang-Gi Choi, Jung Ho Han, Yong-Wan Kim, Junmo Lim, Hwan-Suck Chung
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:International Journal of Molecular Sciences
Subjects:
photodynamic therapy
single-cell RNA sequencing
cancer immunology
humanized PD-1 mice
tumor-infiltrating T cell
Online Access:https://www.mdpi.com/1422-0067/24/18/13913

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https://www.mdpi.com/1422-0067/24/18/13913

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