Identification of KCNJ5 gene an adverse prognosis associated novel onco-ionchannel in Indian pancreatic cancer cohort

Identification of KCNJ5 gene an adverse prognosis associated novel onco-ionchannel in Indian pancreatic cancer cohort

Abstract Background Pancreatic cancer (PanCa) is one of the most lethal cancers (survival ~ 12%). As the conventional therapeutic interventions are mostly futile, a deep understanding of the disease pathophysiology is an urgent need. Ion channels, located on cell membrane, contribute significantly t...

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Bibliographic Details
Main Authors: Akash Bararia, Arunima Maiti, Gourav Ghosh, Deepyaman Das, Debabrata Ghosh Dastidar, Sumit Mukherjee, Shibajyoti Ghosh, Bitan K. Chattopadhay, Sudeep Banerjee, Supriyo Ghatak, Nilabja Sikdar
Format: Article
Language:English
Published: Springer 2025-02-01
Series:Discover Oncology
Subjects:
Pancreatic ductal adenocarcinoma
450 K methylation array
Enriched Pathways
Inward rectifying potassium channel
Druggable protein
Differntially methylated ion channel
Online Access:https://doi.org/10.1007/s12672-025-02001-8

Internet

https://doi.org/10.1007/s12672-025-02001-8

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