Variation along P2RX7 interacts with early traumas on severity of anxiety suggesting a role for neuroinflammation

Variation along P2RX7 interacts with early traumas on severity of anxiety suggesting a role for neuroinflammation

Abstract Emotional stress is a leading risk factor in the development of neuropsychiatric disorders possibly via immune activation. P2X7 receptors promote neuroinflammation, and research suggests a relationship between chromosome region 12q2431, in which the P2X7R gene is located, and development of...

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Main Authors: Zsuliet Kristof, Zsofia Gal, Dora Torok, Nora Eszlari, Sara Sutori, Berta Erdelyi-Hamza, Peter Petschner, Beata Sperlagh, Ian M. Anderson, John Francis William Deakin, Gyorgy Bagdy, Gabriella Juhasz, Xenia Gonda
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-34781-w

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https://doi.org/10.1038/s41598-023-34781-w

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