The TLR2 Binding Neisserial Porin PorB Enhances Antigen Presenting Cell Trafficking and Cross-presentation

Abstract TOLL-like receptor (TLR) ligands activate both innate and adaptive immune cells, while modulating the cellular immune response. The outer membrane protein (OMP) from Neisseria meninigitidis, PorB, is a naturally occurring TLR2 ligand and functions as an adjuvant. Here, we demonstrate that P...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Michael L. Reiser, Munir M. Mosaheb, Christina Lisk, Andrew Platt, Lee M. Wetzler
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: Nature Portfolio 2017-04-01
Цуврал:Scientific Reports
Онлайн хандалт:https://doi.org/10.1038/s41598-017-00555-4