IL-5 and GM-CSF, but Not IL-3, Promote the Proliferative Properties of Inflammatory-like and Lung Resident-like Eosinophils in the Blood of Asthma Patients

IL-5 and GM-CSF, but Not IL-3, Promote the Proliferative Properties of Inflammatory-like and Lung Resident-like Eosinophils in the Blood of Asthma Patients

Blood eosinophils can be described as inflammatory-like (iEOS-like) and lung-resident-like (rEOS-like) eosinophils. This study is based on the hypothesis that eosinophilopoetins such as interleukin (IL)-3 and IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) alter the proliferative...

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Bibliographic Details
Main Authors: Jolita Palacionyte, Andrius Januskevicius, Egle Vasyle, Airidas Rimkunas, Ieva Bajoriuniene, Skaidrius Miliauskas, Kestutis Malakauskas
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cells
Subjects:
asthma
eosinophil
IL-3
IL-5
GM-CSF
proliferation
Online Access:https://www.mdpi.com/2073-4409/11/23/3804

Internet

https://www.mdpi.com/2073-4409/11/23/3804

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