Quantitative Analysis of a Pilot Transwell Barrier Model with Automated Sampling and Mathematical Modeling

In the preclinical phase of drug development, it is necessary to determine how the active compound can pass through the biological barriers surrounding the target tissue. In vitro barrier models provide a reliable, low-cost, high-throughput solution for screening substances early in the drug candida...

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Bibliographic Details
Main Authors: Júlia Tárnoki-Zách, Szilvia Bősze, András Czirók
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/15/11/2646