Exploring hTERT promoter methylation in cutaneous T‐cell lymphomas

Exploring hTERT promoter methylation in cutaneous T‐cell lymphomas

Cutaneous T‐cell lymphomas (CTCLs) are telomerase‐positive tumors expressing hTERT, although neither gene rearrangement/amplification nor promoter hotspot mutations could explain the hTERT re‐expression. As the hTERT promoter is rich in CpG, we investigated the contribution of epigenetic mechanisms...

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Bibliographic Details
Main Authors: Alain Chebly, Joana Ropio, Jean‐Marie Peloponese, Sandrine Poglio, Martina Prochazkova‐Carlotti, Floriane Cherrier, Jacky Ferrer, Yamina Idrissi, Evelyne Segal‐Bendirdjian, Eliane Chouery, Chantal Farra, Anne Pham‐Ledard, Marie Beylot‐Barry, Jean‐Philippe Merlio, Roland Tomb, Edith Chevret
Format: Article
Language:English
Published: Wiley 2022-05-01
Series:Molecular Oncology
Subjects:
cutaneous T‐cell lymphomas
DNA methylation
DNMTi
HDACi
telomerase
TERT
Online Access:https://doi.org/10.1002/1878-0261.12946

Internet

https://doi.org/10.1002/1878-0261.12946

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