Dityrosine Crosslinking of Collagen and Amyloid-β Peptides Is Formed by Vitamin B<sub>12</sub> Deficiency-Generated Oxidative Stress in <i>Caenorhabditis elegans</i>

Dityrosine Crosslinking of Collagen and Amyloid-β Peptides Is Formed by Vitamin B<sub>12</sub> Deficiency-Generated Oxidative Stress in <i>Caenorhabditis elegans</i>

(1) Background: Vitamin B<sub>12</sub> deficiency in <i>Caenorhabditis elegans</i> results in severe oxidative stress and induces morphological abnormality in mutants due to disordered cuticle collagen biosynthesis. We clarified the underlying mechanism leading to such mutant...

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Bibliographic Details
Main Authors: Kyohei Koseki, Aoi Yamamoto, Keisuke Tanimoto, Naho Okamoto, Fei Teng, Tomohiro Bito, Yukinori Yabuta, Tsuyoshi Kawano, Fumio Watanabe
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:International Journal of Molecular Sciences
Subjects:
Alzheimer’s disease
ascorbic acid
<i>Caenorhabditis elegans</i>
collagen
dityrosine crosslinking
oxidative stress
Online Access:https://www.mdpi.com/1422-0067/22/23/12959

Internet

https://www.mdpi.com/1422-0067/22/23/12959

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