Loss of EZH2-like or SU(VAR)3–9-like proteins causes simultaneous perturbations in H3K27 and H3K9 tri-methylation and associated developmental defects in the fungus Podospora anserina

Loss of EZH2-like or SU(VAR)3–9-like proteins causes simultaneous perturbations in H3K27 and H3K9 tri-methylation and associated developmental defects in the fungus Podospora anserina

Abstract Background Selective gene silencing is key to development. It is generally accepted that H3K27me3-enriched heterochromatin maintains transcriptional repression established during early development and regulates cell fate. Conversely, H3K9me3-enriched heterochromatin prevents differentiation...

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Bibliographic Details
Main Authors: F. Carlier, M. Li, L. Maroc, R. Debuchy, C. Souaid, D. Noordermeer, P. Grognet, F. Malagnac
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Epigenetics & Chromatin
Subjects:
Histone methylation
Sexual development
ChIP-seq
Podospora anserina
Online Access:https://doi.org/10.1186/s13072-021-00395-7

Internet

https://doi.org/10.1186/s13072-021-00395-7

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