Epigallocatechin gallate and curcumin inhibit Bcl-2: a pharmacophore and docking based approach against cancer

Abstract The protein Bcl-2, well-known for its anti-apoptotic properties, has been implicated in cancer pathogenesis. Identifying the primary gene responsible for promoting improved cell survival and development has provided compelling evidence for preventing cellular death in the progression of mal...

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Bibliographic Details
Main Authors: Noor Bahadar, Sher Bahadar, Abdul Sajid, Muqeet Wahid, Ghadir Ali, Abdullah Alghamdi, Hakeem Zada, Tamreez Khan, Shafqat Ullah, Qingjia Sun
Format: Article
Language:English
Published: BMC 2024-07-01
Series:Breast Cancer Research
Subjects:
Online Access:https://doi.org/10.1186/s13058-024-01868-9