Movement of cerebrospinal fluid tracer into brain parenchyma and outflow to nasal mucosa is reduced at 24 h but not 2 weeks post-stroke in mice

Abstract Background Recent data indicates that cerebrospinal fluid (CSF) dynamics are disturbed after stroke. Our lab has previously shown that intracranial pressure rises dramatically 24 h after experimental stroke and that this reduces blood flow to ischaemic tissue. CSF outflow resistance is incr...

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Bibliographic Details
Main Authors: K. E. Warren, K. G. Coupland, R. J. Hood, L. Kang, F. R. Walker, N. J. Spratt
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Fluids and Barriers of the CNS
Subjects:
Online Access:https://doi.org/10.1186/s12987-023-00427-2