Structural Analysis of Metabolites of Asiatic Acid and Its Analogue Madecassic Acid in Zebrafish Using LC/IT-MSn

Although zebrafish has become a significant animal model for drug discovery and screening, drug metabolism in zebrafish remains largely unknown. Asiatic acid (AA) and madecassic acid (MA), two natural pentacyclic triterpenoids mainly obtained from Centella asiatica (L.) Urban, have been found to pos...

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Bibliographic Details
Main Authors: Binbin Xia, Lu Bai, Xiaorong Li, Jie Xiong, Pinxiang Xu, Ming Xue
Format: Article
Language:English
Published: MDPI AG 2015-02-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/20/2/3001