An Egg-Derived Sulfated <i>N</i> -Acetyllactosamine Glycan Is an Antigenic Decoy of Influenza Virus Vaccines

Influenza viruses grown in eggs for the purposes of vaccine generation often acquire mutations during egg adaptation or possess different glycosylation patterns than viruses circulating among humans. Here, we report that seasonal influenza virus vaccines possess an egg-derived glycan that is an anti...

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Bibliographic Details
Main Authors: Jenna J. Guthmiller, Henry A. Utset, Carole Henry, Lei Li, Nai-Ying Zheng, Weina Sun, Marcos Costa Vieira, Seth Zost, Min Huang, Scott E. Hensley, Sarah Cobey, Peter Palese, Patrick C. Wilson
Format: Article
Language:English
Published: American Society for Microbiology 2021-06-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00838-21