Could exercise hormone irisin be a therapeutic agent against Parkinson’s and other neurodegenerative diseases?

Parkinson’s disease (PD) is the second most common neurodegenerative disease after Alzheimer’s disease (AD). The pathologic hallmarks of the disease are the loss of dopaminergic neurons of substantia nigra pars compacta and the presence of intraneuronal alpha synuclein (a-syn) aggregates. Clinical f...

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Bibliographic Details
Main Authors: Konstantinos I. Avgerinos, Junli Liu, Maria Dalamaga
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Metabolism Open
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589936823000051