Caryocar villosum attenuates inflammation by inhibiting CXCL1 activation and peripheral hyperalgesia through opioid pathway modulation

Caryocar villosum attenuates inflammation by inhibiting CXCL1 activation and peripheral hyperalgesia through opioid pathway modulation

ABSTRACT The oil of Caryocar villosum is used in Amazonian folk medicine to treat pain and inflammatory conditions. So, we assessed the anti-inflammatory and antinociceptive properties of the ethanolic extract obtained from the fruit peels of this species. The acetic acid-induced writhing, carrageen...

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Bibliographic Details
Main Authors: Gutemberg Lopes SOARES, Lívia Christine Ribeiro HILGENBERG, Giovana Reis BATISTA, Matheus Kleber de Jesus SOUZA, Renata Cristina Mendes FERREIRA, Irismara Sousa SILVA, Tallita Marques MACHADO, Carlos Cleomir de Souza PINHEIRO, Fernanda GUILHON-SIMPLICIO, Andre KLEIN, Andrea de Castro PEREZ, Emerson Silva LIMA, Clarice de Carvalho Veloso MOURA
Format: Article
Language:English
Published: Instituto Nacional de Pesquisas da Amazônia 2022-09-01
Series:Acta Amazonica
Subjects:
pain
antinociception
chemokine
leukocyte recruitment
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672022000300245&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672022000300245&tlng=en

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