Leveraging large observational studies to discover genetic determinants of drug concentrations: A proof‐of‐concept study

Abstract Large, observational genetic studies are commonly used to identify genetic factors associated with diseases and disease‐related traits. Such cohorts have not been commonly used to identify genetic predictors of drug dosing or concentrations, perhaps because of the heterogeneity in drug dosi...

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Bibliographic Details
Main Authors: Maxime Meloche, Grégoire Leclair, Martin Jutras, Essaïd Oussaïd, Marie‐Josée Gaulin, Ian Mongrain, David Busseuil, Jean‐Claude Tardif, Marie‐Pierre Dubé, Simon deDenus
Format: Article
Language:English
Published: Wiley 2022-04-01
Series:Clinical and Translational Science
Online Access:https://doi.org/10.1111/cts.13230